There are several different manners in which to treat breast cancer. Breast cancer can be successfully treated with lumpectomy and IORT or intra-operative radiation therapy. In patients with smaller tumors and of a low grade the tumor can be resected and radiation delivered at the time of the lumpectomy. The breast can be rearranged and closed allowing for an optimal aesthetic outcome. The photograph shown demonstrated oncoplastic reconstruction of a left breast cancer after IORT.