Reconstruction of lumpectomy defects has advanced over the past several years with the implementation of oncoplastic reconstruction techniques. Patients often have questions about how their skin will look following post-lumpectomy radiation therapy. This patient underwent right lumpectomy with post-operative radiation therapy and left breast reduction/mastopexy for symmetry. The right sided scars that underwent radiation therapy have healed better than the non-radiated side. The skin on the right side has also tolerated radiation therapy well. It is important for patients to be compliant with skin hydration therapy during radiation treatment.